Annual report pursuant to section 13 and 15(d)

CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY

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CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY (USD $)
In Thousands, except Share data
Total
USD ($)
Common Stock
USD ($)
Additional Paid-in Capital
USD ($)
Accumulated Deficit
USD ($)
Advisory Board and Consultants
USD ($)
Advisory Board and Consultants
Additional Paid-in Capital
USD ($)
Employees
USD ($)
Employees
Common Stock
Employees
Additional Paid-in Capital
USD ($)
Beginning Balance at Dec. 31, 2008 $ 51,290 $ 17 $ 166,172 $ (114,899)          
Beginning Balance (in shares) at Dec. 31, 2008   171,715,514              
Issuance of common stock under employee stock purchase plan (in shares)   210,048              
Issuance of common stock under employee stock purchase plan 118   118            
Exercise of stock options, net of 58,474 shares tendered in payment of exercise price in 2011 (in shares)   512,875              
Exercise of stock options, net of 58,474 shares tendered in payment of exercise price in 2011 242   242            
Stock-based compensation (in shares)               1  
Stock-based compensation         550 550 6,984   6,984
Repurchase and retirement of common stock (in shares)   (4,531,400)              
Repurchase and retirement of common stock (2,717)   (2,717)            
Net income (loss) (18,673)     (18,673)          
Ending Balance at Dec. 31, 2009 37,794 17 171,349 (133,572)          
Ending Balance (in shares) at Dec. 31, 2009   167,907,038              
Issuance of common stock in private equity offering, net of expenses of $122 (in shares)   14,050,000              
Issuance of common stock in private equity offering, net of expenses of $122 13,928 1 13,927            
Issuance of common stock under employee stock purchase plan (in shares)   62,274              
Issuance of common stock under employee stock purchase plan 63   63            
Exercise of stock options, net of 58,474 shares tendered in payment of exercise price in 2011 (in shares)   1,345,050              
Exercise of stock options, net of 58,474 shares tendered in payment of exercise price in 2011 710   710            
Issuance of restricted stock grants (net of 2,500 shares forfeited)   197,500              
Stock-based compensation         49 49 5,390   5,390
Repurchase and retirement of common stock (in shares)   (65,370)              
Repurchase and retirement of common stock (64)   (64)            
Net income (loss) (10,951)     (10,951)          
Ending Balance at Dec. 31, 2010 46,919 18 191,424 (144,523)          
Ending Balance (in shares) at Dec. 31, 2010   183,496,492              
Issuance of common stock under employee stock purchase plan (in shares)   58,884              
Issuance of common stock under employee stock purchase plan 83   83            
Exercise of stock options, net of 58,474 shares tendered in payment of exercise price in 2011 (in shares)   626,298              
Exercise of stock options, net of 58,474 shares tendered in payment of exercise price in 2011 473   473            
Exercise of warrants (in shares)   132,500              
Exercise of warrants 126   126            
Stock-based compensation         688 688 3,266   3,266
Cancelation of restricted stock(in shares)   (5,000)              
Cancelation of restricted stock 60   60            
Repurchase and retirement of common stock (in shares)   (1,056,106)              
Repurchase and retirement of common stock (1,493)   (1,493)            
Warrants issued to lenders 9,428   9,428            
Net income (loss) 3,893     3,893          
Ending Balance at Dec. 31, 2011 $ 63,443 $ 18 $ 204,055 $ (140,630)          
Ending Balance (in shares) at Dec. 31, 2011   183,253,068