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Exhibit 23.1

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Independent Registered Public Accounting Firm’s Consent

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We consent to the incorporation by reference in this Registration Statement on Form S-3 of our report dated August 15, 2024 relating to the financial statements appearing in the Annual Report on Form 10-K of CytoDyn Inc. for the year ended May 31, 2024. We also consent to the reference to us under the heading “Experts” in such Registration Statement.

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/s/ Marcum llp

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Hartford, CT

July 25, 2025

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