Annual report pursuant to Section 13 and 15(d)

Consolidated Statement of Stockholders' Equity

v3.10.0.1
Consolidated Statement of Stockholders' Equity - USD ($)
$ in Thousands
Total
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Loss [Member]
Accumulated Deficit [Member]
Balance at beginning of period at Dec. 31, 2015 $ 28,115 $ 2 $ 424,422 $ (21) $ (396,288)
Balance at beginning of period (in shares) at Dec. 31, 2015   23,447,003      
Stock-based compensation expense 2,473   2,473    
Net loss (26,671)       (26,671)
Net unrealized gain (loss) on marketable securities 20     20  
Balance at end of period at Dec. 31, 2016 3,937 $ 2 426,895 (1) (422,959)
Balance at end of period (in shares) at Dec. 31, 2016   23,447,003      
Issuance of common stock upon exercise of warrants, value 1,058   1,058    
Issuance of common stock upon exercise of warrants (Shares)   99,207      
Issuance of common stock upon exercise of stock options and incentive awards 2,196   2,196    
Issuance of common stock upon exercise of stock options and incentive awards (Shares)   607,138      
Stock-based compensation expense 4,920   4,920    
Issuance of common stock, value 100,436 $ 2 100,434    
Issuance of common stock, (in shares)   20,255,448      
Net loss (27,557)       (27,557)
Net unrealized gain (loss) on marketable securities (43)     (43)  
Balance at end of period at Dec. 31, 2017 84,947 $ 4 535,503 (44) (450,516)
Balance at end of period (in shares) at Dec. 31, 2017   44,408,796      
Issuance of common stock upon exercise of warrants, value 11,929   11,929    
Issuance of common stock upon exercise of warrants (Shares)   956,845      
Issuance of common stock upon exercise of stock options, value $ 3,571   3,571    
Issuance of common stock upon exercise of stock options (Shares) 750,852 750,852      
Stock-based compensation expense $ 7,013   7,013    
Issuance of common stock, value 135,520 $ 2 135,518    
Issuance of common stock, (in shares)   13,340,000      
Net loss (72,548)       (72,548)
Net unrealized gain (loss) on marketable securities (14)     (14)  
Balance at end of period at Dec. 31, 2018 $ 170,418 $ 6 $ 693,534 $ (58) $ (523,064)
Balance at end of period (in shares) at Dec. 31, 2018   59,456,493