ALACHUA, Fla., Oct. 29, 2018 (GLOBE NEWSWIRE) -- CTD Holdings, Inc. (OTCQB: CTDH), a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical need, announced today that it has filed a patent application titled “Methods for Treating Alzheimer’s Disease.”
“This patent application evidences CTD’s commitment to expanding our clinical program for Trappsol® Cyclo™ for diseases with unmet medical needs,” said N. Scott Fine, CTD’s Chairman and CEO. Mr. Fine added that “this patent application is directed to using hydroxypropyl beta cyclodextrins, including CTD’s Trappsol® Cyclo™, for the treatment of Alzheimer’s Disease, a devastating illness for patients and their families and a growing public health burden in the United States and globally.”
The U.S. Centers for Disease Control and Prevention (CDC) reports that there were 5 million people in the U.S. with Alzheimer’s Disease or dementia in 2014. CDC estimates this number will grow to 13.9 million by 2060.
The patent application covers dosing regimens and routes of administration. The patent application lists co-inventors Sharon H. Hrynkow, PhD, Jeffrey L. Tate, PhD, and N. Scott Fine of CTD Holdings.
Hydroxypropyl beta cyclodextrins have been shown in animal models and cell culture to reduce the formation of amyloid beta, one of the hallmarks of Alzheimer’s Disease.
“With few treatment options available to ameliorate symptoms or slow progression of Alzheimer’s Disease, we look forward to working with clinical partners to explore the potential of Trappsol® Cyclo™ for this indication,” said Dr. Hrynkow, CTD’s Senior Vice President for Medical Affairs.
CTD currently collaborates with the Kerwin Research Center to provide Trappsol® Cyclo™ intravenously to a single patient with late-onset Alzheimer’s Disease on an Expanded Access basis (ClinicalTrials.gov NCT03624842).
About CTD Holdings:
CTD Holdings, Inc. is a clinical-stage biotechnology company that develops cyclodextrin-based products for the treatment of disease. The company’s Trappsol® Cyclo™, an orphan drug designated product in the United States and Europe, is used to treat Niemann-Pick Disease Type C, a rare and fatal genetic disease, on a compassionate use basis as well as in two ongoing formal clinical trials (Clinical Trials.gov NCT02939547 and NCT02912793). Additional indications for the active ingredient in Trappsol® Cyclo™ are in development. For additional information, visit the company’s website: www.ctd-holdings.com
Safe Harbor Statement:
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