Brian Cascio

Division of Corporate Finance

United States Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549-3628

Form 10-K for the fiscal year ended December 25, 2010

Filed February 18, 2011

File No. 001-07882                                                                   

Dear Mr. Cascio:

On behalf of Advanced Micro Devices, Inc. (“AMD” or the “Company”), we confirm receipt of the letter dated August 5, 2011 from the staff (the “Staff”) of the Securities and Exchange Commission (the “Commission”) with respect to the above referenced Form 10-K. We are responding to the Staff’s comment on behalf of AMD, as set forth below. The Staff’s comment is set forth below in bold and numbered to correspond to the numbered comment in the Staff’s letter. AMD’s response follows the Staff’s comment.

Form 10-K for the fiscal year ended December 25, 2010

Certain Relationships and Related Transactions and Director Independence, page 132

August 12, 2011

Page 2

Response: In response to the Staff’s comment, the Company hereby confirms that its expenses related to GLOBALFOUNDRIES’ (GF) wafer manufacturing of $1.2 billion and research and development activities of $114 million represent all payments under the agreement to the related party for the fiscal year ended December 25, 2010. In addition, please be advised that the Company also disclosed in its Quarterly Reports on Form 10-Q for its first two quarters of fiscal 2011 expenses related to GF (please refer to page 6 and page 28 of the respective Quarterly Reports on Form 10-Q for further details). These expenses also represent all payments under the agreement to the related party during these periods.

*        *        *

We respectfully request that if the Staff has any additional questions or comments, please direct them as soon as possible to the undersigned at (650) 463-3060.

Harry A. Wolin, Esq., Advanced Micro Devices, Inc.

Faina Roeder, Esq., Advanced Micro Devices, Inc.